

Neuronal insight to support antidepressant selection
BrightKaire is designed to support the prescriber in identifying the optimal antidepressant for each patient, guided by its effectiveness in each patient's own brain cells, and tailored to their genetic profile. Based on state-of-the-art technology, for the first time we can see how the patient's brain responds to the drug before treatment.
Brightkaire Supports Your Evidence-Based Prescribing for Depression Treatment
With BrightKaire’s “brain-in-a-dish” platform, patient-derived neurons are exposed to a panel of antidepressants. Proprietary AI technology measures neuroplasticity, the biological process behind antidepressant response, enabling prescribers to tailor antidepressant prescriptions to each specific patient. Together with pharmacogenomic analysis, BrightKaire delivers actionable insights to guide personalized treatment planning and optimize medication selection before the first prescription is written.
Functional Drug Response for Each Patient
BrightKaire highlights medications most likely to be effective for your patient, combining neuronal response patterns with pharmacogenomic guidance to support informed, tailored prescribing.
Reduced Trial-and-Error Prescribing
Drug response profiles, together with PGx dosage and interaction insights, help you avoid ineffective or poorly tolerated options, streamlining treatment selection and improving adherence.
Personalized Integrated Insights
By connecting neurobiologically unique insights with genetic and clinical profiles, BrightKaire delivers clinically actionable results that inform efficacy, tolerability, and biomarker relevance.
Clinical Validation & Laboratory Standards
BrightKaire is performed in our CLIA-certified lab meeting standards, ensuring analytical quality, operational rigor and compliance with applicable regulations.
Selected Scientific Publications
Peer-reviewed publications authored or co-authored by NeuroKaire scientists and collaborators provide additional scientific context in precision psychiatry, neuronal modeling, and antidepressant response.
What happens next
Bring BrightKaire Into Your Practice
BrightKaire is now available to clinicians ready to move beyond trial-and-error prescribing. By combining patient-derived neuronal response patterns with pharmacogenomic insights, BrightKaire provides actionable, evidence-driven guidance to optimize antidepressant selection from the very first prescription.
Join the growing community of prescribers transforming care—request a demo today and see how BrightKaire can enhance outcomes for every patient.

Frequently Asked Questions
Clinicians considering prescribing antidepressants to their patients may utilize the BrightKaire™ blood test as a valuable tool to facilitate their decision-making process in finding the right drug for their patients.
Neurokaire's BrightKaire test for depression is currently commercially available. We are CE and CLIA certified and fully operational in the USA, Europe and Israel. If you or someone you know is struggling to find the right antidepressant and would like to benefit from Brightkaire™ visit www.neurokaire.typeform.com/BrightKaire
The BrightKaire™ test is a simple blood test that helps clinicians choose the best antidepressant medication for patients . The test uses a combination of neuronal imaging, genetic, and clinical data to predict how well a patient will respond to different antidepressants and how likely they are to experience side effects. Each patient and their clinician receives a detailed report on how their brain is likely to respond to an assay of 18 antidepressants and various other medications.
The BrightKaire test is composed of two parts:
1. Genetic Testing
This part analyzes genes that affect how your body processes hundreds of different medications. It helps identify how efficiently you might metabolize certain drugs, which may help your provider choose a medication that works better for you.
2. Neuroplasticity Testing
This part assesses how your neurons respond to specific medications in a lab environment, providing insight into your brain’s functional response. The medications evaluated include:
Together, these two components give a more comprehensive picture of how your body and brain may respond to certain antidepressants and related medications.
All of Neurokaire’s commercially available tests are run in CAP Accredited and CLIA Certified labs.
For U.S.-based clients:
Once your order is confirmed, we’ll automatically ship you a BrightKaire collection kit. Inside, you’ll find two blood tubes and a detailed instruction manual for the medical professional performing your blood draw.
You have two options for completing your blood collection:
- Visit a Quest Diagnostics clinic – Bring your kit to your local Quest clinic, where a technician will draw your blood and handle shipping to our lab at no additional cost.
- Schedule an at-home draw – For $60, you may book a licensed professional through TravelLabs to collect your sample from home.
Important: Blood draws must be done only on Monday, Tuesday, or Wednesday to prevent delays in shipping and avoid samples sitting idle over the weekend.
For all other clients: Our team will contact you to organize blood procurement
NeuroKaire™ (formerly Genetika+) is a HIPAA (Health Insurance Portability and Accountability Act) covered entity. Results that contain protected health information will only be shared with the ordering physician and as otherwise permitted by law.
Your patient’s identifiable health information collected through Neurokaire™ is protected in accordance with HIPAA requirements and kept confidential. De-identified data from Neurokaire™ is used to improve the way mental health is diagnosed and treated. De-identified data may be used in research and in the development of new drugs, therapies, and analytical tools. NeuroKaire's™ (formerly Genetika+) notice of privacy practices is available here.
Preliminary results of BrightKaire's™ Pharmacogenetics test will be delivered to the ordering physician approximately 15 business days from the time we receive the sample and order requisition form. Results for the final neuronal neuroplasticity score can take approximately 12 weeks. Our team is working diligently to decrease the time to results, please be patient as we are currently dealing with overwhelming demand.

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