Transforming brain health

An AI-enabled paradigm for precision medicine in CNS diseases

Our Mission

We are transforming brain health and eliminating suffering through the integration of precision medicine in psychiatry and neurology. NeuroKaire’s neuronal readout offers a new window into brain function.

We harness Nobel-Prize winning technology to generate iPSC-derived neurons from each individual, enabling clinicians to identify the optimal medication for each patient based on the unique response of each patient's brain cells combined with genetics and medical history.

Precision Medicine. Realized.

Each individual's own derived brain cells inform their optimal treatment

Powered by Computer Vision

AI and computer vision applied on
multi-modal data for unprecedented accuracy

Comprehensive Biobank and Data repository

A robust repository with hundreds of thousands of data points from diverse patient profiles across multiple conditions

Learn More

our data

Multi-modal insights drive evidence-based care

The largest and most comprehensive databank combining imaging, genomic and clinical data from patient-derived neurons.

1.5M+

Clinical Data Points

2,500+

Microscopy Features

20,000+

RNA Transcripts/Patients

120,000+

Clinical Patients

who we help

We Transform Depression

NeuroKaire (formerly Genetika+) is transforming psychiatry & neurology care by providing patients, physicians, drug developers and researchers, for the first time, an approach to precision medicine through the lense of each patient’s unique neurobiology, with deep actionable mechanistic insight into disease and patient characteristics.

A smiling doctor with a stethoscope around his neck and a clinic in the background.

For Providers

NeuroKaire’s evidence-based tests and services offer the quality and commitment you need to help guide treatment strategies for your psychiatry and neurology diseases' patients.

A happy lady wearing a black coat with an office look in the background.

For BioPharma

From initial discovery to launch of a new therapy, we are your ideal partner to help make your next breakthrough the standard of care.

For Patients

We are committed to providing specific cell-based insights into your psychiatric or neurological disorder to help your doctor guide a personalized care plan.

Our Process

step 1

Patient Sample

The process begins with a simple blood draw, which can be performed in any setting, including the comfort of home.

‍

A rectangle shaped structure having pillars inside it with a white background

Stem Cell Conversion with white background

‍

step 2

Stem Cell Conversion

Using Nobel-Prize winning technology, peripheral blood cells are reprogrammed into pluripotent stem cells through the induction of key developmental protein factors.

step 3

Brain in a Dish

Stem cells are treated with a carefully designed sequence of growth factors to generate specific neuronal subtypes, reflecting the brain regions most relevant to the disease.

Patient-derived neurons are then exposed to various compounds or challenges. Key features of neuronal function, activity, and communication are analyzed using cutting-edge computer vision and deep learning algorithms.

‍

A cube shaped dotted structure having white background

‍

step 4

AI Predictions

Powerful AI tools are used to combine the various features into a single score that reflects the compound’s efficacy on the specific patient’s neurons.

This score is then combined with clinical and demographic features of the patient for environmental effects and potential drug adverse effects, as well as with the patient's pharmacokinetic profile, resulting in a combined score for drug responsiveness.

step 5

Deep
Understandings

Using patients' own derived neurons allows for the first time, insight into drug efficacy in individual patients, even before first-in-human studies.

Using the combination of imaging and molecular analysis, we obtain a deep understanding of the mechanism of action of each compound, its interaction with clinical and environmental factors, and comparison with existing or in-development drugs.

The outputs are actionable insights from mechanistic underpinnings in individual patients.

‍

Side view of brain with white background

How it works

step 1

Patient Sample

The process starts with a standard patient blood collection. Blood samples can be obtained in any setting including the comfort of an individual’s home.

step 2

Stem Cell Conversion

Through a process that induces protein expression of key factors found in early embryos, peripheral blood cells are reprogrammed to pluripotent stem cells using Nobel prize winning technology.

step 3

Brain in a Dish

Once created, these stem cells are treated with a sequence of unique growth factors to generate specific neuronal subtypes that reflect the brain region most relevant for disease.

Patient-derived neurons are then exposed to compounds or other challenges and features relevant for neuronal function, activity, and communication are analyzed using state-of-the-art computer vision and deep learning algorithms

step 4

AI Predictions

Powerful AI tools are used to combine the various features into a single score that reflects the compound’s efficacy on the specific patient’s neurons.

This score is then combined with clinical and demographic features of the patient for environmental effects and potential drug adverse effects, as well as with the patient pharmacokinetic profile, resulting in a combined score for drug responsiveness.

step 5

Deep Understandings

Using patient’s own derived neurons allows for the first time insight into drug efficacy in individual patients, even before first-in-human studies.

Using the combination of imaging and molecular analysis, we obtain deep understanding of the mechanism of action of each compound, its interaction with clinical and environmental factors, and comparison with existing or in-development drugs.

The outputs are actionable insights from mechanistic underpinnings in individual patients.

Our Partners

Awards & Recognitions

NeuroKaire (formerly Genetika+) is proud to be recognized by organizations around the world for our impact on the healthcare ecosystem.

Testimonials

I truly feel that they care about my well-being and are dedicated to helping me achieve the best possible outcome. Their approach allows them to design a personalized treatment plan that perfectly suits my needs. This level of attention and individualized care has made a significant difference in my journey.

Emma, 24

What impressed me the most about NeuroKaire was how easy the process was and how they even connected me to the right provider. I didn’t have to leave my home for extra appointments, and they worked around my schedule. Their personalized insights have made a tremendous difference.

Austin, 32